I’m not an expert, but looking at the research paper this is just blocking one one particular vitamin a receptor, so most functions of vitamin A would not be affected. Once concern is that this particular receptor (RAR-alpha) is partially responsible for neutrophil production, although they didn’t notice any changes in animal tests, possibly because those receptors are tucked away inside your bone marrow. Still could be a concern with long term use though…
An exciting development, but the drug affects the body’s use of Vitamin A so I think they need more studies looking for non-reproductive side effects.
Night blindness and immune dysfunction are associated with vitamin A deficiency.
I’m not an expert, but looking at the research paper this is just blocking one one particular vitamin a receptor, so most functions of vitamin A would not be affected. Once concern is that this particular receptor (RAR-alpha) is partially responsible for neutrophil production, although they didn’t notice any changes in animal tests, possibly because those receptors are tucked away inside your bone marrow. Still could be a concern with long term use though…