I’m not an expert, but looking at the research paper this is just blocking one one particular vitamin a receptor, so most functions of vitamin A would not be affected. Once concern is that this particular receptor (RAR-alpha) is partially responsible for neutrophil production, although they didn’t notice any changes in animal tests, possibly because those receptors are tucked away inside your bone marrow. Still could be a concern with long term use though…

As a longtime donor of the project, last I checked there were still concerns about the reversability of the treatment

It’s pure speculation what deals are or aren’t being offered Mangione. I’d be surprised if he isn’t offered one at some point.

If I’m in an elevator alone with a woman or something I will usually just give a friendly nod and adopt a very relaxed posture, like leaning against the wall. The youtuber Contrapoints talked about this exact scenario in one of her videos (a black man whistling in the elevator so she wouldn’t feel scared) and it made me more aware of it.

On a Lemmy I’m always the person who thinks people are overreacting or exaggerating. But this really does seem like the end of firefox as a privacy champion (which, apart from being nonprofit, was my only real reason for using it). I think I will make a donation to ladybird.

Another thing: their acceptable use policy straight up forbids viewing pornography or graphic violence. No nuance or exceptions.

Are you talking about Furiosa the spinoff movie or Furiosa in Mad Max? I have never heard a single complaint about Furiosa in Mad Max

Titanic literally the box office champ for a decade with a female lead (close to 50-50 to be fair). Terminator 2 as well, and Mad Max Fury road, 2 of the greatest action movies of all time (you can fight me but, name aside, that story is all about Furiosa). Those movies work because the female leads are just good. The selling point isn’t that they have women in them, the selling point is they are really really good movies.

Edit: and Kill Bill, where a lot of critics call The Bride (the lead of the movie) the greatest movie character of all time.

I only use bluesky to follow a couple of ukraine war news accounts. It’s very good for that purpose. I don’t interact at all or read comments, twitter was always an absolute cesspool and I assume bkuesky is as well, or will be if it ever replaces twitter

You would say there is overwhelming evidence that Musk is a Nazi? I’d like to see it.

No don’t you get what I’m saying? Let’s say my acquaintance Jim is a Nazi. I, mistakenly, think he is not a Nazi. Someone calls Jim a Nazi and I say, “no, Jim’s cool, he’s not like that”. That would make me WRONG. It would not make me a NAZI. People get fooled all the time, a fact everyone in this thread seems to be forgetting, and that fallibility applies just as much to Musk’s accusers as his defenders.

I do think he wasn’t zeig heiling. So do most people in the real world who aren’t hooked in to leftist social media 24/7.

Anyways you’re missing the point. The point is that OPs brother thinks Musk didn’t do it. So are you really going to cut someone out of you life for having the majority opinion that someone isnt a Nazi and therefore is defensible?

“You cannot be a good person until you actively work for the liberation of people, instead of voting against their rights.”

“OK what if you think fetuses are people”

“But they arent”

“But I think they are, so I think I am morally righteous”

“But they aren’t and therefore you are a bad person”

Just using abortion as an example… I am strongly pro-choice myself but I dont think people are bad just because they are pro-life. Misguided? Sure, but thats hugely different than being evil. There is a ton of space in society for good people to have different political views. The notion that everyone who disagrees with you politically is a bad person is childish.

So according to you his brother is wrong. He made a mistake in interpereting a hand gesture. You would cut him out of your family for that?

As far as the Musk thing goes: I won’t even get into whether or not Musk was really trying to do a Nazi salute. Personally, I don’t think he was, Musk denies it, plenty of Jewish people and Jewish advocacy groups also say they don’t think it was intentional. But the important thing is, your brother doesn’t think it was intentional. So, at worst, he has committed the crime of being naive, and there’s a very good chance that he’s right and you’re wrong. If he said, yes Musk did a Nazi salute on purpose and then defended that, that would be way over the line. But honestly he sounds like a pretty run of the mill libertarian/conservative. And I will die on the hill that the vast majority of libertarians and conservatives are good people, even if I disagree with them politically.

Read it here, hopefully not paywalled https://www.reuters.com/technology/chinas-rednote-what-you-need-know-about-app-tiktok-users-are-flocking-2025-01-15/

Rednote with multiple SIMULTANEOUS video feeds sounds like a whole new level of brain rot

-Very skilled songwriter. I don’t necessarily like all her stuff but I legitimately think she’s the best songwriter (meaning, composing music and writing lyrics) of her generation. Probably since Bruce Springsteen or Billy Joel.

-Very attractive and a good performer

-Well connected in the music industry let her get an early start/inside track

-obsessed with being popular. I don’t mean that in a negative way, but her primary objective with her music is to please as many people as possible. I think the documentary “Miss Americana” on Netflix explains that very well-at one point she straight up says “I just want people to like me” or something like that. That means her music/career has always focused on mass appeal as opposed to making more… limited-appeal music like most artists do at some point in their career

-she’s kept a remarkably clean image even through being famous for close to two decades. It’s very telling that the worst thing her haters can say about her is “but her plane uses a lot of carbon!” This means parents let kids listen to her, brands love her as a sponsor, nobody boycotts her, etc.

-one last thing, I think people love her songs because they feel like they’re true. Her songs have a very intimate, almost confessional quality that a lot of artists strive for buy often comes off as fake.