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Cake day: July 6th, 2023

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  • Does gout come from consuming animal products? Hmm, I hadn’t heard that, before.

    Opposite actually - fructose intake, alcohol intake (same pathway as fructose in liver), advanced glycation end products (glucose intake) are the major drivers of gout.

    https://doi.org/10.1016/B978-0-12-821617-0.00004-8 Section 7.3 if you would like to know more (overwhelmingly so) - it’s available on the normal 🦜 sites.

    Basically the old connection that meat can drive uric acid a bit and uric acid is a component of gout isn’t actually helpful, during a active flare up avoiding meat can help reduce uric acid levels a tiny bit but it does nothing to address the systemic cause of the gout in the first place. i.e. Watermelons have a high water content but are not causal in drownings, but avoid eating watermelons while actively drowning… same thing





  • jet@hackertalks.comtoVideos@lemmy.worldCharlie Kirk is a Racist
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    5 days ago

    As you all know by now, on September 10th, Charlie Kirk was murdered on a college campus in Utah. While I’ve always vehemently disagreed with Kirk on 95% of issues, and while I stand by everything I said about him in this video, he didn’t deserve to die. Nobody deserves to be murdered or physically harmed because of their words and beliefs.

    When I found out he was shot, I had the misfortune of seeing the video. It was the worst thing I’ve ever seen. I had to stop doing homework. I couldn’t pay attention in class. It shook me to my core. It affected me a lot more than the Trump shooting, and not just because this time someone had actually died. The President of the United States will always be a target. If the President actually gets shot, it’s shocking and horrifying, but it usually means that the Secret Service just had a bad day. But when a political commentator, an internet celebrity who held no public office, is murdered in cold blood, something is deeply wrong with your country.

    My thoughts are with Charlie and his family.

    Pinned comment from the YouTube channel, thehadirahin.









  • De Arrow Title

    The Prisoner’s Dilemma and its real life applications

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    Summary

    This video explains the famous game theory problem known as the Prisoner’s Dilemma, tracing its origins, applications, and profound implications in real-world scenarios such as nuclear deterrence during the Cold War and cooperation among animals. It starts by recounting the historical context of the Cold War nuclear arms race, highlighting how the United States and the Soviet Union were trapped in a strategic dilemma similar to the Prisoner’s Dilemma, where both sides defected (built up nuclear arsenals), ending in a suboptimal and dangerous stalemate. The game itself involves two players choosing to either cooperate or defect, with defection always being the rational choice in a single round, even though mutual cooperation would yield better outcomes.

    The video then explores how repeated interactions transform the dilemma. Robert Axelrod’s famous computer tournaments in the 1980s tested various strategies in an iterated Prisoner’s Dilemma setting, with the simplest strategy—Tit for Tat—emerging as the most successful. Tit for Tat cooperates initially, then mimics the opponent’s previous move, promoting reciprocity and punishing defection without holding grudges. Axelrod identified four key qualities for success: being nice (never the first to defect), forgiving, retaliatory (punishing defection immediately), and clear (easy to understand).

    The video further discusses the evolutionary implications of these findings, showing how cooperation can evolve even among selfish individuals or organisms, using examples like impalas grooming each other. It also addresses the role of noise (errors in perception or action), which can trigger retaliatory cycles, and how a slightly more forgiving strategy can mitigate this problem. Finally, it relates these insights back to real-world diplomacy, such as the gradual nuclear disarmament during the late Cold War, illustrating how incremental cooperation with verification can succeed where all-at-once agreements fail. The video closes by emphasizing the importance of strategic decision-making and cooperation, inviting viewers to develop problem-solving skills through learning platforms like Brilliant.

    Highlights

    • ⚔️ The Prisoner’s Dilemma models conflicts from Cold War nuclear arms races to everyday cooperation dilemmas.
    • 💣 The Cold War nuclear arms buildup mirrored the Prisoner’s Dilemma, where rational defection led to mutual destruction risk.
    • 🤝 Axelrod’s iterated Prisoner’s Dilemma tournaments revealed that “nice” and “forgiving” strategies outperform complex, nasty ones.
    • 🐾 Cooperation in nature, like impalas grooming each other, can be explained through repeated Prisoner’s Dilemma interactions.
    • 🔄 Tit for Tat’s success lies in its simplicity: start cooperating, then mimic your opponent’s last move.
    • ⚠️ Noise in communication can cause retaliatory cycles, but generous forgiveness helps break these cycles.
    • 🌍 Cooperation can emerge and spread even in selfish populations, influencing everything from biology to international relations.

    Key Insights

    • 🎯 Rational Defection vs. Collective Benefit: In a single round of the Prisoner’s Dilemma, defection is the dominant strategy because it maximizes individual payoff regardless of the opponent’s choice. However, when both players defect, they receive a suboptimal payoff compared to mutual cooperation. This paradox highlights why rational individual choices can lead to collectively worse outcomes, exemplified by the Cold War nuclear arms race where both superpowers stockpiled weapons, increasing global risk and expense.
    • 🔁 The Power of Iteration: Repeated interactions fundamentally change the strategic landscape. Unlike one-shot games, iterated Prisoner’s Dilemma scenarios allow players to build reputations, learn from past moves, and condition their behavior on previous outcomes. This creates incentives for cooperation to evolve because defection may be punished in future rounds, and cooperation may be reciprocated, leading to better long-term payoffs. Axelrod’s tournaments empirically demonstrated this by simulating thousands of rounds between strategies.
    • 🤝 Tit for Tat: Simplicity and Effectiveness: The simplest strategy—Tit for Tat—won Axelrod’s tournaments by starting cooperatively, then mirroring the opponent’s last move. This strategy embodies the balance between niceness (never initiating defection), retaliation (punishing defection immediately), forgiveness (returning to cooperation if the opponent does), and clarity (being predictable), which fosters trust and discourages exploitation. Its success reveals that complex and deceptive strategies are often outperformed by straightforward reciprocity.
    • 🌿 Evolutionary Origins of Cooperation: The iterated Prisoner’s Dilemma provides a framework to explain how cooperation can arise naturally in populations of self-interested individuals or organisms without altruism. Cooperation can spread if cooperators cluster together and gain mutual benefits, eventually overtaking defectors. This is supported by ecological simulations and observed behaviors in animals, such as impalas grooming to remove ticks, where repeated interactions promote mutual aid despite immediate costs.
    • 🔍 Role of Noise and Forgiveness: Real-world interactions are noisy—misinterpretations or accidental defections can trigger cycles of retaliation. Tit for Tat, while effective in noise-free settings, performs poorly when errors occur because retaliations escalate. Introducing probabilistic forgiveness (e.g., defecting only some of the time in response) helps break these cycles, maintaining cooperation despite misunderstandings. This insight underscores the importance of flexibility and error tolerance in stable cooperation.
    • 🌐 Implications for International Relations: The Cold War arms reduction agreements illustrate a practical application of iterated Prisoner’s Dilemma principles. Instead of a one-time disarmament (a single-shot dilemma), the US and Soviet Union engaged in a series of incremental disarmament steps with verification, enabling mutual trust and cooperation over time. This gradual, reciprocal approach prevented defection and helped reduce nuclear stockpiles, demonstrating how game theory informs diplomacy and peace-building strategies.
    • 🧠 Beyond Zero-Sum Thinking: Many people equate winning with beating others, but the Prisoner’s Dilemma and Axelrod’s findings show that cooperation creates win-win outcomes where all participants gain more together than by competing. Unlike zero-sum games (e.g., chess), life often offers opportunities where the “banker” is the environment or society itself, and players gain by unlocking collective benefits. This reframes conflict resolution and problem-solving as finding cooperative strategies rather than purely competitive ones.

    Extended Analysis

    The video demonstrates how the Prisoner’s Dilemma is not merely an abstract mathematical curiosity but a fundamental model capturing the tension between individual rationality and collective welfare. Its relevance spans nuclear strategy, biological cooperation, social interactions, and economic behavior. While defection maximizes short-term individual gain, it risks long-term collective disaster, highlighting the importance of trust, reputation, and repeated engagement in fostering cooperation.

    Axelrod’s tournaments serve as a landmark experiment in computational social science and political theory. That the simple Tit for Tat strategy outperformed complex, deceptive approaches challenges assumptions that cunning or trickery necessarily triumph. Instead, it suggests that transparent, reciprocal behavior is evolutionarily stable and socially beneficial. The qualities of niceness, forgiveness, retaliatory response, and clarity identified by Axelrod resonate with moral norms and common-sense fairness, linking game theory to ethical principles.

    The evolutionary simulations further connect these ideas to biology, showing how cooperative traits can spread even in populations of selfish agents, provided there is repeated interaction and spatial or social clustering. This insight bridges disciplines from mathematics to ecology, psychology, and sociology.

    The discussion of noise introduces realism into the model, recognizing that misunderstandings and errors are inevitable in real systems. Adjusting strategies to be forgiving while maintaining deterrence prevents destructive retaliation spirals, a lesson applicable to human diplomacy and conflict management.

    Finally, the video emphasizes that cooperation is not about altruism but enlightened self-interest, where acting “nice” and cooperative ultimately benefits oneself. It encourages viewers to recognize opportunities for collaboration in real life and to approach conflicts with strategies that reward mutual benefit rather than zero-sum competition.

    This comprehensive exploration of the Prisoner’s Dilemma and Axelrod’s work enriches our understanding of strategic decision-making, encouraging more thoughtful and effective cooperation in diverse domains from international politics to everyday human interactions.


    This summary and analysis provide a deep understanding of the video’s content while highlighting its broad significance, offering insights into the mechanics and implications of the Prisoner’s Dilemma beyond the original transcript.



  • I have no data for this, so i’m just speculating wildly (and accepting this will be a unpopular conjecture):

    Lemmas - Things I have data for

    • Metabolic dysfunction is endemic in the population (96% westerners)
    • Metabolic dysfunction impacts hormones, especially sex hormones
    • Aromatase happens at elevated levels in metabolically compromised people
    • This can manifest as man-boobs, love-handles, chin hair, etc
    • Metabolic dysfunction is principally caused by diet.

    Speculation - Things I have no data for

    • There is probably some connection between sexuality and hormones
    • There is probably some connection between sexuality and life-long diets

    This means there might be a interesting correlation you could discover. However, I don’t think anyone would fund this type of research, or publish it - it would cause controversy needlessly.


    Seeing a population prefer vegetables doesn’t speak to cause and effect, it could be a cultural appreciation for being healthy and vegetables are mostly seen as healthy by most groups.





  • Is it possible to never go to a fast food chain?

    We have the physical addiction to glucose, but you have overcome that before

    We have the habitual triggers, something in your life makes you think of your old addiction, those you have to find a way to get past, maybe the snacking

    We have the situational triggers, seeing a place, going past a place, triggers old addictive cravings, this is where having a buddy you can call and talk it out can be helpful.

    If you are willing to wear a CGM all the time, you can have a buddy monitoring it and get alerts if it goes outside of a predefined range (say 6.5) so your buddy can help you deal with the recovery

    When you fall off the wagon before, you mentioned fast food, but what is different the month before falling off and the day you fall off?